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Cirrhosis Management Prevention in Futures

Progress in the hepatic cirrhosis prevention and management of cirrhosis continues. Research is underway to determine the mechanism of scar formation in the liver and how the healing process can be halted or even reversed. The newest and best treatments for viral diseases of the liver are being developed to prevent progression to cirrhosis. Prevention of viral hepatitis by vaccination, which is available for hepatitis B, is in development for hepatitis C. The treatment of complications of cirrhosis are continuously developed and tested. Finally, the research aims to identify new proteins in the blood can detect liver cancer early or predict which patients will develop liver cancer.

Hepatic Cirrhosis Disease Brief Information

• Cirrhosis disease is a liver complication disease leading to loss of liver cells and irreversible scarring of the liver.
• Alcohol and viral hepatitis C and hepatitis C are common causes of cirrhosis, although there are many other causes.
• Cirrhosis can cause bruising, weakness, loss of appetite, yellowing of the skin (jaundice), fatigue and itching.
• The cirrhosis diagnosis can be suggested by history, blood tests and physical examination, and can be confirmed by liver biopsy.
• The complications of liver cirrhosis are edema and ascites, variceal bleeding, spontaneous bacterial peritonitis, hepatic encephalopathy, hypersplenism, hepatorenal syndrome, Hepatopulmonary syndrome and liver cancer.
• Treatment of cirrhosis is designed to prevent more damage to the liver, treatment of complications of cirrhosis, and prevention or early detection of liver cancer.
• Liver transplantation is becoming an important option for treating patients with advanced cirrhosis.

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Prevention Liver Cancer Detection and Transplantation

In this session, I will explain in detail about liver cancer prevention and early detection of liver cancer, and cirrhosis liver transplantation .

Prevention liver cancer and early detection of liver cancer

There are several types of disease that causes liver cirrhosis associated with a particularly high incidence of liver cancer, for example, hepatitis B and C, and would be useful to detect liver cancer and early surgical treatment or Liver transplantation can cure the cancer patient. The difficulty is that the methods available for research are only partially effective in identifying, at best, only 50% of patients in a curable stage of cancer. Despite the partial effectiveness of screening, most patients with cirrhosis, hepatitis B and C, are reviewed annually or every six months with liver ultrasound and measurement of proteins produced by cancer in the blood, for example , alpha-fetoprotein.

Cirrhosis Liver Transplantation

Cirrhosis is irreversible. Liver function in many patients become progressively worse despite treatment and complications of cirrhosis will increase and become difficult to treat. Therefore, when advanced cirrhosis, liver transplantation is often the only option for treatment. Recent advances in transplant surgery and drugs to prevent infection and rejection of the transplanted liver had significantly improved survival after transplantation. On average, over 80% of patients who receive transplants are alive after five years. Not all people with cirrhosis is a candidate for transplantation. Furthermore, there is a shortage of livers for transplantation, and usually have a (long months or years) to wait before a liver transplant to make it available. Therefore, measures to slow the progression of liver disease and to treat and prevent complications of cirrhosis are of vital importance.

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Hepatitis A Virus Infection Prevention Tips

Many ways to prevent Hepatitis A Virus Infection, such as :
1. Get vaccinated against hepatitis A, if your travel plans, work, health, or lifestyle puts you at risk for exposure to hepatitis A (HAV). For more information, see what increases the risk of this category.
2. Develop habits of hygiene.
- Make sure you and all family members wash their hands with soap and warm water after using the toilet and before preparing or eating food.
- wash dishes in hot soapy water or a dishwasher.
- discourage children from putting objects in their mouths, especially when they share toys with other children.
- Do not eat or drink anything that you think may have been prepared in filthy conditions.
3. Protect yourself before flying and when on his journey. If you are traveling to some of the world where sanitation is poor or if hepatitis A is a known problem, consult your doctor about vaccination against hepatitis A, immune globulin (Ig) or a combination vaccine against hepatitis A and B. Always drink bottled water or boil water before drinking. Avoid tap water or untreated well water or drinks with ice. And do not eat raw foods (such as unpeeled fruits or vegetables).
4. Crus not eat shellfish or cooked. If molluscs that live in water have been contaminated with feces containing the virus of hepatitis A infected molluscs May.

Child care workers should be educated about how often prevent the spread of hepatitis A prevention. Although children infected with hepatitis A may have little or no symptoms, can infect other people, including child care workers and other adults who may develop more severe symptoms. To prevent the spread of hepatitis A virus HAV, the child care workers must :
- Use plastic (not latex, because of the risk of allergic reaction), disposable gloves when changing diapers.
- Wash children’s hands, and then use a new pair of gloves when changing diapers for another child.
- Clean the diaper changing surface after each mutation.
- Talk to your doctor about getting vaccinated against HAV.

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Diabetes Cirrhosis Treatment to Prevent Liver Damage

The treatment of diabetes cirrhosis treatment include : prevent further damage to the liver, treatment of complications of cirrhosis, early detection and prevention of liver cancer, and liver transplantation.

And I will explain more detail the diabetes cirrhosis treatment steps, starting from how to prevent further damage to the liver.

• Eat a balanced diet and a daily multivitamin. PBC patients with impaired absorption of fat soluble vitamins may need supplements of vitamins D and K.
• Avoid drugs (including alcohol) that causes liver damage. All patients with cirrhosis should avoid alcohol. Most patients with cirrhosis induced by alcohol experience an improvement in liver function with abstinence from alcohol. Even patients with hepatitis B and C can significantly reduce liver damage and slow the progression to cirrhosis with alcohol withdrawal.
• Avoid anti-inflammatory drugs (NSAIDs, eg ibuprofen). Patients with cirrhosis may experience a worsening of liver and kidney with NSAIDs.
• Reducing hepatitis B and hepatitis C using anti-viral drugs. All patients with cirrhosis from chronic viral hepatitis are candidates for drug therapy. Some patients may experience a severe deterioration of liver function and / or intolerable side effects during treatment. Therefore, decisions to treat viral hepatitis should be individualized after consultation with physicians experienced in treating liver diseases (hepatologists).
• Removal of blood from patients with hemochromatosis to reduce iron levels and prevent further damage to the liver. In Wilson’s disease, medications can be used to increase copper excretion in the urine to reduce levels of copper in the body and prevent further damage to the liver.
• Remove the immune system with drugs such as prednisone and azathioprine (Imuran) to reduce inflammation of the liver in autoimmune hepatitis.
• Treat patients with primary biliary cirrhosis with a preparation of bile acid, ursodeoxycholic acid (UDCA), also called ursodiol (Actigall). The results of an analysis that combines results from several clinical trials have shown that UDCA improved survival in patients with PBC during 4 years of treatment. The development of portal hypertension has also been reduced by UDCA. Importantly, despite evident benefits, UDCA treatment delays progression and above all, not a cure for PBC. Other drugs such as colchicine and methotrexate may also have benefits for subgroups of patients with PBC.
• Patients with cirrhosis of immunizing against infection with hepatitis A and B to prevent a serious deterioration of liver function. There is currently no vaccine available for immunization against hepatitis C.

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Prevention of Hepatitis A Using Vaccine

The vaccine against hepatitis A (Hepatitis A Vaccine) is the most effective means of preventing infection of hepatitis A virus (HAV). The hepatitis A vaccines provides 94% to 100% protection if you have two shots of vaccine.

Immunization with the hepatitis A vaccine against hepatitis A is recommended for:
- All children from age 1. Two separate doses are given at least 6 months apart. The United States Centers for Disease Control and Prevention made this recommendation in 2006. Many children and adolescents have not had the hepatitis A vaccine.
- Adolescents and children who have not had the vaccine against hepatitis A and are in the following situations:

• An epidemic of the disease has occurred recently.
• They live in a community or state that has established routine immunization because the disease occurs more frequently than in other areas.

- People with health travel, work or lifestyle puts them at risk of exposure. This includes:

• Those planning a trip to a foreign country where sanitary conditions are poor and hepatitis A is common.
• People who use illegal drugs.
• Men who have sex with men.
• People who work with monkeys that are infected and those who work with the virus in a research context.
• People with long-term (chronic) liver disease.
• Who are awaiting or have undergone a liver transplant.
• Persons with hemophilia or related disorders in blood clotting.

A combination hepatitis vaccine (Twinrix vaccine) that prevents hepatitis B and hepatitis A is available for persons over 18 years.

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