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The Prognosis of Lung Cancer and Outcome

lung-cancer_prognosisThe prognosis of lung cancer relates to the likelihood of cure or prolongation of life (survival) and depends on where the cancer is localized tumor size, presence of symptoms, lung cancer and overall health the patient. Lung cancer prognosis, also known as pronostic du cancer du poumon en France, lungenkrebs prognose in Deutschland, la prognosi del cancro del polmone in Italia, El pronóstico de cáncer de pulmón en España.

SCLC growth was the most aggressive of all lung cancers, with a median survival of only two to four months after diagnosis without treatment. (In other words, two to four months, half of all patients have died.) However, the CCP is also the type of lung cancer more sensitive to radiotherapy and chemotherapy. Because SCLC spreads quickly and is available at the time of diagnosis, methods such as surgical excision or localized radiation therapy are less effective in the treatment of this tumor. However, when chemotherapy is used alone or in combination with other methods, survival time can be extended from four to five times, but all patients with SCLC, only 5% -10% are alive five years after diagnosis. Most of those who survive have limited stage SCLC.

In non-small cell lung cancer (NSCLC), the results of standard treatment are generally poor in all but the most localized cancers can be surgically removed. However, in stage I cancers that can be removed completely, five-year survival approaches 75%. Radiation therapy may produce a cure in a small minority of patients with NSCLC and leads to relief of symptoms in most patients. In advanced disease, chemotherapy offers modest improvements in survival time, but overall survival rates are poor.

The overall prognosis for lung cancer is poor compared with other cancers. Survival rates for lung cancer are generally lower than those for most cancers, with a total rate of five year survival for lung cancer by about 16% to 65% for colon cancer, 89% breast cancer and more than 99% for prostate cancer.

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Posted by tata    Date: Saturday, October 17, 2009

Categories: Cancer

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Overview of Lung Cancer Stages

lung-cancer-stages-doctorsWhen diagnosed with lung cancer, the pathologist assigned a type (not lung cancer or lung cancer) and a stage for cancer. The setting is a formal notation means that the spread of cancer and determine the type of treatment recommended by his oncologist. Lung cancer stages also known as Las etapas del cáncer de pulmón, Ciclo di cancro del polmone, lungenkrebs stufen, stades du cancer du poumon in some countries. Importantly, the staging is only used to determine the most appropriate treatment and does not indicate the prognosis.

Fewer, less advanced cancer. For example, cancer stage I cancer is early may and will have spread from their place of origin. Cancer stage IV indicates advanced cancer and may occur in the lungs or other areas of the body (metastasis).

Lung cancers are divided into two types, non-small cell cancer cell lung cancer and small cell lung, according to their cellular characteristics. The staging is different for the two types. In general, the number assigned to the stage of cancer, including tumor characteristics (size, if it has spread), lymph nodes (if the tumor has spread to them, and which ones), and if the tumor ’s is spread by organs of distant metastases. You may see this referred to as the TNM system for tumor, nodes, and metastasis. The American Society of Clinical Oncology, said the system of staging and provides illustrations.
Forecast

It is important to remember that there are treatments for lung cancer, no matter what stage of cancer. Treatment decisions vary depending on the condition of each patient and may also be influenced by the strength of the patient, general health, coexisting diseases and the ability to tolerate certain treatments.

Staging of non-small-cell lung cancer (NSCL cancer): staging for NSCLC using global I-IV, so the earlier and IV are the last. Evaluation of the tumor, lymph nodes and metastases were included in the global arena.

  • Stage I: The first stage of lung cancer. The tumor is found in one lung and has not spread to lymph nodes.
  • Stage II: The tumor has spread to lymph nodes found in the lungs of the environment.
  • Stage IIIA: The tumor has spread to lymph nodes outside the lung, where the surface of the trachea, including the chest wall and diaphragm on the same side as the cancer began.
  • Stage IIIB: The tumor has spread to lymph nodes in the lung face to face or neck.
  • Stage IV: tumor has spread to other parts of the lungs or body.

Cancer staging small cell lung cancer (SCLC cancer) : stage lung cancer small cell stage is classified as limited or extensive.

  • Limited stage: The tumor is found in one lung and nearby lymph nodes.
  • Wide: the tumor has spread beyond the lung and other organs.

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Posted by tata    Date: Monday, October 5, 2009

Categories: Cancer

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Different Types of Lung Cancer in The World

type-lung-cancerThere are any different the types of lung cancer (lung cancer types, or tipos de cáncer de pulmón, tipi di cancro del polmone, types de cancer du poumon, lungenkrebs-typen) in the world. Bronchogenic carcinomas, better known as lung cancer deadly disease (carcinoma is another term for cancer), are broadly classified into two types : lung cancer small cell (SCLC) and non-cancer, small cell (NSCLC). This classification is based on the microscopic appearance of tumor cells. Both types of cancer growth and spread in different ways and may have different treatment options, so a distinction between these two types is important.

SCLC represents approximately 20% of lung cancers are the most aggressive and fastest growing of all lung cancers. CPM are closely related to smoking, with only 1% of these tumors in non-smokers. SCLC spreads quickly to many places in the body and are most often discovered after they have spread widely. Referring to a specific cell appearance, often seen by examining the samples under a microscope SCLC, these cancers are sometimes called oat cell carcinoma.

NSCLC lung cancer the most frequent, representing approximately 80% of all lung cancers. NSCLC can be divided into three main types which are named according to the type of cells in the tumor as below :

- Adenocarcinomas

The adenocarcinomas are the most frequently observed in NSCLC in the U.S. and up to 50% of NSCLC. While adenocarcinomas are associated with smoking and lung cancer, this pattern is seen both in non-smokers who develop lung cancer. Most adenocarcinomas arise in areas outside the lungs or peripheral. Bronchioloalveolar carcinoma is a subtype of adenocarcinoma, which often takes place at several sites in the lungs and spreads along the preexisting alveolar walls.

Squamous cell carcinoma

Squamous cell carcinoma were once more common than adenocarcinomas, currently representing around 30% of NSCLC. Also known as squamous cell carcinoma, squamous cell carcinoma are more common in the chest area in the central bronchi.

- The large cell carcinomas

Large cell carcinomas sometimes referred to as undifferentiated carcinomas, are the most common NSCLC low.

- Mixtures of different types of NSCLC are also seen.

Other cancers types may arise in the lung and these guys are much less common than NSCLC and SCLC, and together represent only 5% -10% of lung cancers :

- Bronchial carcinoids make up approximately 5% of lung cancers. These tumors are usually small (3-4 cm or less) when diagnosed and occur more frequently in people younger than 40 years. Non-smoking, carcinoid tumors can metastasize, and a small proportion of these tumors secrete hormones and substances that can cause specific symptoms related to the hormone produced. Carcinoids and dissemination in general, grow more slowly than lung cancer, and many are detected early enough to be amenable to surgical resection.

- Cancers of the supporting tissues of the lung, such as vascular smooth muscle or blood cells involved in immune response may occur rarely in the lungs.

As mentioned above, metastatic tumors in the major organs are often in the lungs. Tumors anywhere in the body can spread to the lungs, either by blood through the lymphatic system or directly to nearby organs. Metastatic tumors are more often multiple, scattered throughout the lung, and is concentrated in peripheral regions rather than the central regions of the lung.

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Posted by tata    Date: Thursday, September 24, 2009

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Causes of Lung Cancer Information

smoking-cause-lung-cancerMaybe some people ask, what causes of lung cancer?  There are many lung cancer causes, such as smoking or to be passive smokers, asbestos fibers, because radon, or the family predisposition, lung disease from family, air pollution or history of the lung cancer family can make lung cancer cause (lungenkrebs verursacht, provoque le cancer du poumon, provoca il cancro ai polmoni, causa cáncer de pulmón).

Smoking

The incidence of lung cancer is closely linked to smoking, with approximately 90% of lung cancers caused by snuff. The risk of lung cancer increases with the number of cigarettes smoked over time, doctors refer to this risk in terms of pack-years history of smoking (number of packs of cigarettes smoked per day multiplied by the number of years). For example, a person who has smoked two packs of cigarettes a day for 10 years has a pack of 20, smoking history year. Although the risk of lung cancer increases even with a 10 pack year history of smoking, those who have stories 30-lot-of one year or more are regarded as having the greatest risk of developing lung cancer. Among people who smoke two or more packs of cigarettes a day, seven people who die from lung cancer.

Pipe and cigar smoking can also cause lung cancer, but the risk is not as high as with cigarette smoking. As a person who smokes a pack of cigarettes per day had a risk of developing lung cancer is 25 times higher than a non-smoker, pipe smokers and cigar has a risk of lung cancer is about five times the non – smoking.

Snuff smoke contains over 4,000 chemical compounds, many of which have been shown to cause cancer, or cancer. The two major carcinogens in tobacco smoke are chemicals known as nitrosamines and polycyclic aromatic hydrocarbons. The risk of developing lung cancer decreases each year after quitting, as normal growth of cells and replace damaged cells in the lungs. In former smokers, the risk of developing lung cancer begins to approach that of a non-smoker for 15 years after quitting.

Passive smoking

Passive smoking, or inhaling the smoke of smokers suck life and work of shared premises, is also a risk factor for developing lung cancer. Research has shown that non-smokers living with a smoker have a 24% increase in risk of developing lung cancer compared to other non-smokers. It is estimated that 3,000 deaths from lung cancer occur each year in the United States that are attributable to passive smoking.

Asbestos fibers

Asbestos fibers are silicate fibers that can persist throughout life in lung tissue after exposure to asbestos. The workplace is a common source of exposure to asbestos fibers, asbestos was widely used in the past that the thermal and acoustic insulation. Today, the use of asbestos is restricted or prohibited in many countries including the United States both lung cancer and mesothelioma (cancer of the pleura, the lung and the lining of the cavity abdominal peritoneum) are associated with exposure to asbestos. Smoking greatly increases the likelihood of developing lung cancer linked to asbestos-exposed workers. Asbestos workers who smoke have a fivefold risk of developing lung cancer than non-smokers and asbestos workers who smoke have a risk that is 50 to 90 times higher than non smoking.

Radon

Radon is a gas, chemically inert gas that is produced by the natural decay of uranium. Uranium decays to form products, including radon, which emit a type of ionizing radiation. Radon is a known cause of lung cancer, and about 12% of deaths from lung cancer attributable to radon, or 15,000-22,000 deaths from lung cancer each year in the United States, making that radon the second leading cause of lung cancers in the U.S. As with exposure to asbestos, smoking increases concomitantly the risk of lung cancer from exposure to radon. Radon gas can travel through soil and enter homes through cracks in the foundations, drains, sewers or other openings. The United States Environmental Protection Agency estimates that one in 15 homes in the U.S. contain dangerous levels of radon gas. Radon is invisible and odorless, but can be detected with simple test kits.

The Familial predisposition

Although most lung cancers are associated with the consumption of tobacco and snuff, the fact that not all smokers eventually develop lung cancer suggests that other factors such as individual genetic predisposition may play a role in the the etiology of lung cancer. Many studies have shown that lung cancer is more likely to occur in smokers and nonsmokers of the family of those who have lung cancer than the general population. Recent research has identified a region on the long (q) arm of chromosome 6, which may contain a gene that confers a greater susceptibility to develop lung cancer in smokers.

Lung diseases

The presence of certain lung diseases, including chronic obstructive pulmonary disease (COPD) is associated with increased risk (four to six times the risk of a non-smoker) to develop lung cancer, even after the concomitant effects tobacco are excluded.

History of lung cancer

Survivors of lung cancer are more at risk than the general population to develop lung cancer second. Survivors of cancers of small cell lung (NSCLC see below) have an additional risk of 1% -2% per year to develop lung cancer second. Among survivors of non-lung cancer, small cell (CPM, see below), the risk of developing certain cancers secondary approaches 6% annually.

Air pollution

Air pollution from power plants, vehicles and industry can increase the likelihood of developing lung cancer among exposed individuals. Up to 1% of deaths from lung cancer are due to inhalation of contaminated air, and experts believe that prolonged exposure to highly polluted air may pose a risk of developing lung cancer similar to that of passive smoking.

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Posted by tata    Date: Monday, September 21, 2009

Categories: Cancer

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