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Obsessive Compulsive Disorder OCD, Definition and Frequency in the World

An obsessive-compulsive disorder OCD is when intrude repeatedly thoughts and actions that are recognized by those involved, although as senseless, against whose appearance they are not able to defend themselves. Will not yield to this compulsion to feel the affects mainly an unbearable tension.

Obsessive-compulsive disorder causes likely to be disturbed by interaction of biological and psychological factors, there seems to one of the metabolism of certain neurotransmitters in brain. On the other constraints may be a form of anxiety management are considered, such as an intense fear of being infected with an infectious disease can lead to an extreme washing behavior. In the treatment of obsessive-compulsive disorder psychiatric and psychotherapeutic techniques are used, such as the elimination of coercive action, and deal with anxiety result.

Definition of Obsessive Compulsive Disorder  ( OCD )

As OCD ( Obsessive Compulsive Disorder ) ideas and actions are known to occur to a human being. Although the parties recognize these thoughts or impulses for action is absurd and try to resist, however, they can not defend himself against their occurrence. If the pressure does not yield to those affected often feel unbearable tension Read more…

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Treatment of Lung Cancer Therapy for Healthy

The treatment of lung cancer, also known as lung cancer treatments and therapy can result in surgical removal of the tumor, chemotherapy or radiotherapy, and combinations of these treatments. The decision on which treatments are appropriate for a given individual should take into account the location and extent of the tumor and the patient’s general health.

As with other types of cancer treatment can be provided that the allegations curative (removal or eradication of cancer) or palliative (measures that are not able to cure cancer, but may reduce pain and suffering). More than one type of treatment may be prescribed. In such cases, therapy is added to enhance the effects of primary therapy is known as adjuvant therapy. An example of adjuvant treatment with chemotherapy or radiation therapy after surgery to remove a tumor, to be sure who killed the tumor cells.

Lung Cancer Surgery

Surgical removal of the tumor is usually performed for limited stage (stage I or, sometimes, phase II) and NSCLC (non-small-cell lung cancer) is the treatment against cancer that has not spread beyond the lung. Approximately 10% -35% of lung cancers can be surgically removed, but the withdrawal does not always translate into a cure, because the tumors have already spread in May and may occur at a later date. Among those who are isolated, slow-growing cancer of the lung removed, 25% to 40% are still alive five years after diagnosis. Surgery may not be possible if the cancer is near the trachea or if you have other serious diseases (like heart or lung disease) that limit their ability to tolerate surgery. The operation was performed less often because SCLC tumors are less likely to be located in an area that can be eliminated.

The surgical lung cancer procedure chosen depends on the size and location of the tumor. Surgeons must open the chest wall and may perform a lung wedge resection (removal of part of one lobe), lobectomy (removal of one lobe) or pneumonectomy (removal of an entire lung). Sometimes lymph nodes in the region of the lungs are removed (lymphadenectomy). Surgery for lung cancer is a major surgery requiring general anesthesia, hospitalization and follow-up care for weeks or months. After surgery, patients may experience difficulty breathing, shortness of breath, pain and weakness. The risks of surgery are complications due to hemorrhage, infection and complications from general anesthesia.

Lung Cancer Radiation

Therapy radiation may be used as a treatment for both NSCLC (non-small-cell lung cancer) and SCLC (small cell lung cancer). Radiation therapy of lung cancer uses high-energy X-rays or other radiation to kill cancer cells from dividing. Radiotherapy may be administered in curative treatment, palliative treatment (using low doses of radiation that have curative regimes), or as adjuvant therapy in combination with surgery or chemotherapy. The radiation is delivered either externally, using a machine that aims radiation at cancer, or internally by placing radioactive material in sealed containers in the area of the body where the tumor is located. Brachytherapy is a term used to describe the use of a small pellet of radioactive material placed directly in cancer or in the air near the cancer. This is usually done through a bronchoscope.

Radiotherapy lung cancer may be given if a person refuses surgery if the tumor has spread to areas such as the lymph nodes or trachea, making surgical removal impossible, or if a person has other conditions that make too sick to go through major surgery. Radiation therapy is usually only reduce the tumor or the limits of its growth when given alone, however, in 10% -15% of people that leads to a long-term remission and palliation of cancer. Combining radiation therapy with chemotherapy may increase survival when given chemotherapy. External radiation therapy, in general, can be performed on an outpatient basis, while internal radiotherapy requires a short hospital stay. A person who has a serious lung disease, in addition to lung cancer may not be able to receive radiotherapy in the lungs. A type of external radiation called “Gamma Knife” is sometimes used to treat brain metastases only. In this procedure, the multiple radiation beams are focused on the tumor for a few minutes to several hours, while the head is held in place by a rigid structure.

For external beam radiation, a process called simulation is necessary before treatment. Using CT, computers and precise measurements, simulation maps the exact location where the radiation is delivered, called the treatment field or port. This process usually takes 30 minutes to two hours. The external radiation therapy in general, it takes four or five days a week for several weeks.

Radiation therapy does not increase risk of major surgery, but can have unpleasant side effects such as fatigue and lack of energy. A small number of white blood cells (making a person more vulnerable to infection) and low levels of platelets in the blood (blood clotting more difficult) can also occur with radiotherapy. If the digestive organs are in the area exposed to radiation, patients may experience nausea, vomiting or diarrhea. Radiotherapy May irritate the skin in that area, but the irritation usually improves with time after treatment.

Lung Cancer Chemotherapy

Both non-small-cell lung cancer (NSCLC) and CPM can be treated with chemotherapy. Chemotherapy refers to the administration of drugs that inhibit the growth of cancerous cells by killing them or preventing them from dividing. Chemotherapy can be administered alone as adjuvant therapy to surgery or in combination with radiotherapy. If a number of chemotherapy drugs have been developed, the drugs of the class of drugs known as platinum have been most effective in the treatment of lung cancer.

Chemotherapy is the treatment of choice for most CPM, because these tumors are very common in the body when diagnosed. Only half of those with SCLC survive for four months without chemotherapy. With chemotherapy, their survival time increased from four to five times. Chemotherapy alone is not particularly effective in the treatment of non-small-cell lung cancer (NSCLC), but when have metastatic NSCLC, it may prolong survival in many cases.

Chemotherapy may be given in pill form as intravenous infusion, or a combination of both. Chemotherapy treatments are usually given on an outpatient basis. A combination of drugs is given in a series of treatments, called cycles for a period of weeks or months, with breaks between cycles. Unfortunately, chemotherapy drugs also kill normal dividing cells in the body, causing unpleasant side effects. Damage to blood cells may cause increased susceptibility to infections and difficulties related to blood coagulation (bleeding or bruising easily). Other side effects include loss, fatigue, weight gain, hair loss, nausea, vomiting, diarrhea and mouth sores. Side effects of chemotherapy depend on the dose and combination of drugs used and can vary from person to person. Drugs have been developed that can treat or prevent many side effects of chemotherapy. Side effects usually disappear during the recovery phase of treatment or after its completion.

Prophylactic cranial irradiation

Small cell lung cancer (SCLC) often spreads to the brain. Sometimes people with SCLC, which responds well to treatment, are treated with radiation to treat quickly spread to the head brain (called micrometastases) is not yet detectable with CT or MRI and no symptoms yet. Brain radiation therapy can cause problems with short-term memory, fatigue, nausea and other side effects.

Treatment of recurrence

Lung cancer that has returned after treatment with surgery, chemotherapy and / or radiation therapy is called recurrent or relapsed. If recurrent cancer is confined to a site in the lungs, can be treated by surgery. Relapsed tumors do not usually respond to chemotherapy drugs administered previously. As platinum-based drugs are generally used in the initial chemotherapy of lung cancer, these drugs are not useful in most cases of recurrence. A type of chemotherapy called second-line chemotherapy is used to treat recurrent cancer previously treated with chemotherapy, and a series of second-line chemotherapy have proven effective in prolonging survival. People with lung cancer are quite recurrent to tolerate the treatment are also good candidates for experimental therapies (see below), including clinical trials.

Targeted therapy

An alternative to standard chemotherapy is the drug erlotinib (Tarceva), which can be used in patients with ( NSCLC non-small-cell lung cancer ) who no longer respond to chemotherapy. Specific call is a drug, a drug that specifically target cancer cells, causing less damage to normal cells. Erlotinib targets a receptor protein called epidermal growth factor (EGFR), which helps cells to divide. This protein is found in abnormally high levels on the surface of certain types of cancer cells, including many cases of non-small cell cancer of lung cells. Erlotinib is taken orally as tablets.

Among other efforts targeted therapy known as the fight against drugs that block angiogenesis, the development of new blood vessels in cancer. Without blood vessels that carry oxygenated blood adequate cancer cells to die. Anti-angiogenic drug bevacizumab (Avastin) has recently been found to prolong survival in lung cancer in advanced stage when added to standard chemotherapy. Bevacizumab is administered intravenously every two to three weeks. However, since this medication may cause bleeding, is not suitable for use in patients who are coughing up blood, if lung cancer has spread to the brain, or those receiving anticoagulant therapy (diluent blood “) drugs. Avastin is also used in cases of squamous cell cancer, because it causes bleeding of this type of lung cancer.

Photodynamic therapy (PDT)

Therapy newer used for different types and stages of lung cancer (and some other cancers) is photodynamic therapy. In photodynamic therapy, an agent of photosynthesis (as a porphyrin, a naturally occurring substance in the body) is injected into the bloodstream of a couple of hours before surgery. Meanwhile, the deposition agent itself selectively in rapidly growing cells like cancer cells. Then follows a procedure in which the physician applies a certain wavelength of light through a handheld wand directly to the site of the cancer and surrounding tissues. Light energy activates the photosensitizing agent, causing the production of a toxin that kills tumor cells. PDT has the advantage to precisely target the cancer site, is less invasive than surgery and can be repeated on the same site if necessary. The disadvantages of PDT is that it is only useful in the treatment of cancers that can be achieved with a light source and is not suitable for the treatment of cancer spread. The investigation is ongoing to determine the effectiveness of photodynamic therapy in lung cancer.

Radio Frequency Ablation (RFA)

Radiofrequency ablation is studied as an alternative to surgery, especially in cases of lung cancer early. In this new type of treatment involves inserting a needle through skin cancer, usually under the direction of TC. Radiofrequency (electrical) energy is transmitted to the tip of the needle where it produces heat in the tissues, killing the cancerous tissue and the closure of small blood vessels that cancer feed. RFA is usually not painful and has been approved by the Food and Drug Administration of the United States to treat certain types of cancers including lung cancer. Studies have shown that this treatment may prolong survival similar to surgery, when used to treat early stage lung cancer, but without the risks of major surgery and prolonged recovery time associated with major surgical procedures .

The experimental treatments

As no treatment is currently available that is very effective in treating lung cancer, patients can offer a range of treatments that are still being tested, which means that doctors have not yet sufficiently d ‘information to decide if these treatments must be accepted forms of treatment for lung cancer. New drugs or new combinations of drugs are tested in the so-called clinical trials, which are studies that evaluate the effectiveness of new drugs, compared with treatments that are already widely used. Experimental treatment known as immunotherapy, are being considered that involve the use of vaccine-related therapies or other therapies that seek to use the body’s immune system to fight cancer cells.

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Hepatic Cirrhosis Complication Symptoms and Signs Part 2

Previously, we have discussed about signs and symptoms of hepatic cirrhosis complications such as edema and ascites, spontaneous bacterial peritonitis (SBP), and Bleeding esophageal varices in Part 1. Now we will discuss the continuation of hepatic cirrhosis complication symptoms and signs such as hepatic encephalopathy, hepatorenal syndrome, hepatopulmonaire syndrome, hypersplenism and hepatocellular carcinoma (liver cancer) details as below.

Hepatic Encephalopathy

Some of the proteins in food that escapes digestion and absorption is used by bacteria normally present in the intestine. While the utilization of protein for their own purposes, bacteria that cause substances emitted in the intestine. These substances can be absorbed by the body. Some of these substances, eg ammonia, can have toxic effects on the brain. Normally, these toxic substances are transported from the intestine into the portal vein to the liver where they are eliminated from the blood and detoxification.

As mentioned above, when cirrhosis is present, liver cells can not function normally, either because they are damaged or because they have lost their normal relationship with the blood. In addition, some blood in the portal vein bypasses the liver through other veins. The result of these anomalies is that toxic substances can be removed by the liver cells, and instead, toxic substances accumulate in the blood.

When toxic substances accumulate sufficiently in the blood, brain function is disrupted, a condition called hepatic encephalopathy. Sleeping during the day instead of night (reversal of normal sleep pattern) is one of the first symptoms of hepatic encephalopathy. Other symptoms include irritability, inability to concentrate or perform calculations, memory loss, confusion, depression, or levels of consciousness. Ultimately, severe hepatic encephalopathy leading to coma and death.

Toxic chemicals also cause the brain of patients with cirrhosis very sensitive to drugs that are normally filtered and detoxified by the liver. The dose of many drugs that are normally liver detoxification should be reduced to avoid toxic accumulation in cirrhosis, particularly sedatives and drugs used to promote sleep. Alternatively, medications may be used which need not be decontaminated or disposed of the body by the liver, for example, drugs that are eliminated by the kidneys.

Hepatorenal Syndrome

Patients with cirrhosis can develop an intensification of hepatorenal syndrome. This syndrome is a serious complication in which kidney function is reduced. This is a malfunction in the kidneys, i.e. no physical damage to the kidneys. In contrast, the reduction function is due to changes in how blood flows through the kidneys themselves. Hepatorenal syndrome is defined as the progressive inability of the kidneys to clear substances from the blood and produce adequate amounts of urine, but some other important functions of the kidneys, such as salt retention are maintained. If liver function or a healthy liver is transplanted into a patient with hepatorenal syndrome, the kidneys usually start working normally. This suggests that reduced renal function is the result of accumulation of toxic substances in the blood when the liver fails. There are two types of hepatorenal syndrome. An error occurs gradually in recent months. The other is quickly over a week or two.

Hepatopulmonaire Syndrome

More rarely, some patients with advanced cirrhosis may develop hépatopulmonaire syndrome. These patients may have difficulty breathing because of certain hormones released in advanced cirrhosis causes the lungs to function abnormally. The fundamental problem in the lungs is not enough blood flows through tiny blood vessels in the lungs that are in contact with the alveoli (air sacs) of the lungs. The lung blood is diverted around the alveoli and can not collect enough oxygen in the alveoli. Consequently, the patient has trouble breathing, especially with exertion.

Hypersplenism

The spleen normally acts as a filter to remove more red blood cells, white cells and platelets (small particles that are important for blood clotting.). The blood that flows in the rate reaches the blood in the veins of the intestine. With increasing pressure in the portal vein in cirrhosis, which blocks blood flow further and further into the spleen. Blood “backs and accumulates in the spleen, the spleen and swell in size, a condition known as splenomegaly. Sometimes, the spleen is so swollen that causes abdominal pain.

As the spleen, cells from the blood leaks and more and more until the number of platelets in the blood are reduced. Hypersplenism is the term used to describe this condition, and is associated with a low number of red blood cells (anemia), low white blood cell count (leukopenia), and / or a low platelet count (thrombocytopenia). Anemia can cause weakness, infections can cause leukopenia, thrombocytopenia and may inhibit blood clotting and cause prolonged bleeding.

Hepatocellular Carcinoma ( liver cancer )

Cirrhosis due to a cause increases the risk of primary liver cancer (hepatocellular carcinoma). Principal means that the tumor originates in the liver. A secondary liver cancer is one that comes from other parts of the body and spread (metastasize) to the liver.

The most common symptoms and signs of primary liver cancer are abdominal pain and swelling, enlarged liver, weight loss, fever. In addition, cancers of the liver can produce and release a number of substances, including those that cause an increase in red blood cells (polycythemia), blood sugar (hypoglycemia) and high calcium levels (hypercalcemia).

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10 Bad Habits Which Destroy The Brain

Love your brain to avoid brain damage, and very good if you re-look at your habits for granted, but a negative impact to your brain. A healthy brain makes our bodies healthy, thus reducing expenses for medical doctor visits or hospital center.

1. Not want to do breakfast
Many people underestimate the breakfast. And not consume anything in the morning caused a decline in the level of sugar in the blood. This led to a lack of input of nutrients to the brain that finally ended in the decline of the brain. The best breakfast in the morning is not a heavy foods such as fried rice special, but enough water and a glass of fresh juice. Compact and useful for the body!

2. Eat more
Too much to eat up the brain circuits often leads to the decline of mental power. So, eating a normal portion. Familiarize yourself with how to stop eating before you’re stuffed.

3. Smoking
If smoking has many adverse effects, was everyone would know. And one of the many harmful effects of tobacco were discovered here. Smoking is terrifying effect on the brain! Imagine the human brain may be narrowed and ultimately lost its function because it is laborious hood. So when parents, even children, however, we are easily infected Alzheimer (Alzheimer’s dementia is a disease).

4. Too much sugar consumption
Too much will prevent the oral absorption of protein and nutrients that the body malnutrition and brain development disruption. Therefore, reducing the consumption of your favorite sweets.

5. Air pollution
The brain is part of the body to absorb the air most. Too long in the environment due to air pollution makes the brain work less efficiently. Because air pollution can interfere with breathing, your brain and body health.

6. Deprivation of sleep
Sleep for the brain a chance to rest. Often neglect to sleep for brain cells to die from exhaustion. But do not get too much sleep because it can make you become lazy and slow. Should sleep 6-8 hours a day for healthy and fit.

7. Includes a person’s head in her sleep
Sleeping with the head covered is a bad habit that is very dangerous because the carbon dioxide produced during sleep the brain is focused so polluted. Do not be surprised if in time the brain becomes damaged.

8. Thinking too hard when sick
Work or study hard when these conditions are not suitable for your body also exacerbates the ineffectiveness of the brain. Not well known, you should rest and not forsir your brain.

9. Lack of brain to encourage
Think is the best way to train the brain works. Not think will make the brain shrink and ultimately does not work optimally. Laborious reading, music and games (chess, Scrabble, etc.) to get your brain used to think positive and creative.

10. Rarely talk
Intellectual conversations often take a good effect on the brain. So do not be too proud to be quiet. Conversation quality is very good for your health.

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Definition Diabetes Mellitus Deadly Disease

Diabetes Mellitus

What is Diabetes Mellitus? Diabetes Mellitus, some people also known Diabetes as sugar illness, also means sugar flow, since the urine tastes sweet not treated diabetes patients (in earlier times to the diagnostic position a taste sample was taken). This concerns a disturbance of sugar metabolism, with which the cells of the body can take up grape sugar (glucose), transported in the blood, not sufficiently. It is not thereby to the cells as energy source meeting demand at the disposal.

Glucose (dextrose) is the primary cell of nutrients in the blood. Above all, the brain is dependent on the constant supply of glucose, as well as muscle and fat cells feed on them. The body always tries a sufficient supply of glucose in the blood ready to. The blood glucose concentration varies throughout the day.

It can be added glucose by the cells and processed, is the hormone insulin needed. After a carbohydrate-rich meal, insulin is released into the blood. It docks to the insulin receptors of cells and ensures that the cell walls are permeable to glucose. In addition to its great importance for the utilization of glucose from the diet, the hormone insulin also shows effects on lipid metabolism and utilization of amino acids that are the building blocks of proteins.

Insulin is produced in the pancreas (Pancreas). The approximately twelve inches long gland below the stomach serves two functions: first, the pancreas is approximately 0.5 to 1.5 liters daily digestive secretions and releases it into the small intestine. Secondly, the pancreas is the production of insulin.

The cells, where insulin is produced, which are named after their discoverer Paul Langerhans islands of Langerhans (or islet cells or beta cells). They are insular groups spread across the entire gland. Particularly abundant are found in the tail of the pancreas (tail of the pancreas) to. A healthy adult has about one million of these islet cells.

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