Myasthenia Gravis

Details of Myasthenia Gravis Diagnosis

myasthenic diagnosisIn view of the many Myasthenia Gravis patients in United States, Canada, Australia, England, France and Japan, which must live for many years without names for their complaints, it did not operate perhaps, here one (very amateur) to provide overview of the different myasthenia gravis diagnostic methods. In front is referred to which reacts the mg also within the range of the diagnosis very differently, with each method can come it with Myasthenia Gravis patients (MG patients) to negative results! Myasthenia Gravis diagnosis such as :

  • Ice cube sample

This variant is less suitable for an exclusion myasthenia gravis diagnosis, but can give nevertheless certain notes for the further search – and above all it is suitable for “home use” ! It is occasionally used in ocular MG: the drooping eyelids are just chilled with an ice cube. Often, the eyelids may be subsequently opened significantly. Also known as “first aid” used in everyday life (when swallowing altered) with a cold drink.

  • Muscle retaining test

There are various muscle tests for myasthenia gravis diagnosis, with which the duration of the retaining forces is measured. Most frequently the following tests are used :
Simpson test: View upward for at least one minute, ptosis (hanging upper eyelids) can trigger or reinforce
Arm leg rate time: in standing the arms straight before the body are held stretched, , in the supine position with one leg in the 45o angle is increased. Measured is the holding time (the one with that of healthy individuals is compared).

  • EMG

With this myasthenia diagnosis method a nerve is electrically stimulated, and measured the reactions of the appropriate muscle following from it. Customarily are 5 to 10 consecutive current pulses -with MG patients the reaction curve falls clearly off (with the first impulse good reaction, with the further ever more weakly becoming). This method is applied to different muscles – ideally there, which already occur in everyday complaints.
Besides the “normal” EMG, there is the single fiber EMG, in which the reaction can be very targeted, individual muscle fibers are reviewed.

  • Tensilon test

With this tensilon test a fast effective medicine is squirted, which causes a completely clear improvement of the symptoms with mg within fewer minutes. The Tensilon test is partly used with the EMG combined.

  • Anti-body test

In the special laboratory, the blood is tested for specific antibodies against Acethylcholin receptors. Also, this test is negative in many MG, however, is currently a test on a further machine specific auto-antibodies in development.

  • Muscle biopsy

The changes in the receptors can be visualized in the laboratory.

  • Chest CT

The chest CT is not directly suitable for the myasthenia diagnosis of MG, but as with many MG the thymus is significantly increased and there are even some thymomas, this process is used to illuminate the upper body.

  • Curare test

Curare test Is used only in very rare cases, curare increased the MG symptoms quite clearly.

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Posted by tata    Date: Sunday, September 13, 2009

Categories: Myasthenia Gravis

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Myasthenia Gravis in Generalized Symptoms

The symptoms of myasthenia gravis generalized signs are :
- Head / neck
Head cannot be held well upright, supporting with the hand or leaning emergency little. Head cannot be raised in upside-down position or held
- Shoulders / arms
Wash working overhead difficult to impossible (hair, blow-dry, brushing, washing hanging, etc.), turn the car hard (5. course!), wearing of ethnical unreliable, opening and closing heavy doors with full-body application possible
- Hand
Fingers can not be individually lifted, holding Ethnical uncertain, frequently dropping, object can not be lifted, spidery handwriting, difficult stretches of the fingers, fine motor skills is Restricted, fingers every-day work is difficult or impossible (e.g. when handling, rolling cigarettes, typing, needlework, can openers, bread lubrication, safe cover windows, turn keys to open glass, take wallet out of his pocket close) … and it is amazing how many myasthenia gravis MG patients (myasthenic) can’t do that.
- Legs
Difficulties the stair rise and upward gradients to move (as well as expectant), unsteady gait, shuffling, stumbling, long course not possible in severe cases may need to be a wheelchair (preferably with electric drive, as it usually also the strength in arms and not Handen sufficient to secure the wheelchair to move). Support of the arms necessary when rising from a chair, frequently falls without outer occasion.
- Trunk muscles, bad body attitude, sitting slumped
- Sphincter
Even if many physician doctors say the opposite, Urinary incontinence occurs in many Myasthenia Gravis patients. Either as special urgency, as soon as one “must”, or however by losing a bending etc. urine with coughing.

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Posted by tata    Date: Wednesday, September 9, 2009

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Signs Myasthenia Gravis Bulbar Symptoms

There are some signs of myasthenia gravis bulbar symptoms, please check it out :
- Talk : don’t escape from air by the nose, the usual division of  breath when speaking no longer fits. Babbling. Speech is low, indistinct and blurred, less expressive intonation, clumsy tongue.
- Listen : worse hearing, increased sensitivity to noise
- Tongue : frequently, on the tongue biting, food can be transported in the mouth can not adequately as the pharynx, to remove food particles between teeth and cheek wall difficult to restrictions on speech.
- Whistles : notes are not cleanly taken, pursing of the lips is not possible, air escapes through the nose.
- Chewing : firm or softer foods may not be completely chewing, biting on the tongue or cheek.
- Swallow : food remains stuck in the esophagus (which can be painful and uncomfortable), choking, gagging, belching the food share with me, drinks / foods fall into the nose when swallowing.
- Lips : be wiped away can not be reliably concluded (e.g. to rinsing after the tooth flash), spoons cannot be sharpened and fork no more cannot become “wiped off”, restrictions when speaking, cheeks can no more not be blown up, saliva runs from the mouth for whistling any longer, less correctly mobile when kissing.
- Breath : breathing is unusually strenuous or tedious, shortness of breath, breathing heavier than when lying in an upright position, cough without force.
- Mime : sliding out smile (corners of the mouth can not reliably increase), distorted face in laughter, gives an entirely immobile facial expression , MG provides independent from the real mood of tired, arrogant or sad.
- Singing : difficulties, the tone to take and hold on myasthenia-gravis patients, Expressive and modulation capability to let the voice, the sound spectrum is restricted.

After we got explanation about signs of myasthenia gravis bulbar symptom, I will write about Myasthenia Gravis generalized symptoms next. I hope you can check at myasthenia hospital centre or myasthenia gravis medicals in United States (New York, California, Texas, Illinois, Arizona or other states), Canada, Japan, France, Italy, Netherlands, Russia, Poland, United Kingdom, Australia or other medical doctors at your country.

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Posted by tata    Date: Monday, September 7, 2009

Categories: Myasthenia Gravis

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Signs of Myasthenia Gravis Ocular Symptoms

myasthenia gravis symptomsThere are some myasthenia general symptoms, for example : feel fatigue, increased need for sleep, much needed rest, general weakness, low muscle tone, reduction of muscle substance. Difficulties in finding the right words to speaks confusion of right and left, thinking is harder (these problems are probably due to general fatigue as in healthy individuals, the cognitive abilities are Restricted if you are tired).

Other myasthenia gravis general symtpoms are : muscle tremors and pains may occur occasionally during exercise and suggest an overload of the muscles (may have to occur in most banal other function, because the muscles just no longer) correctly.

Signs of Myasthenia Gravis Ocular Symptoms :

- Ptosis and hanging lids
Eyelids, which can no longer be completely open. Can occur unilaterally or bilaterally. Range from the almost imperceptible slopes up to the almost complete closure of the lid. Offset by a tendency-to-back of the head and raised eyebrows.
- Blurred vision on Myasthenic patient
The setting of the eyes close or far away is also done by muscles that act in this case, the lens even change its curvature. It is necessary for vision in the very near as well as in the far field, a voltage of the corresponding muscles. The rest of these muscles is equivalent to a visual distance of about 0.5 to 2 meters. A failure in the muscles, there may be a delay when looking from near to come to television and seeing to permanent problems with the sharp. Glasses can possibly help, but the necessary spectacles can very often another.
- Unsteady glance
Difficulties facing long to keep, it happen on Myasthenia gravis patients.
- Lack of eyelids
Caused by a weakness of the lower eyelid, the eyes can no longer close completely. Often combined with a reflex that let the eye-ball tip on closing the eyes upward. It can happen on myasthenics, so you can check it at your nearest medical doctor or myasthenia hospital.
- Double vision
Caused by a weakness of eye muscles. The eyeball is moved by six muscles, and both eyeballs need to be synchronized with each other, plenty of opportunity for margins!

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Posted by tata    Date: Saturday, September 5, 2009

Categories: Myasthenia Gravis

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Beware Myasthenia Gravis Symptoms

Myasthenia AwarenessThe Myasthenia may be felt in many muscles. It’s often the small, thin muscles and to remember which does not sound human, which they need it at all. In principle, all muscles can be affected, we can consciously move, so it called voluntary or striated muscles. Not affected is the so called smooth muscle, which can be moved only by the autonomic nervous system. That is, for example, the muscles of the stomach and intestines. And also the heart muscle is not beeintrachtig by the Myasthenia Gravis symptoms (which is indeed barred, but represents a special form of striated muscle and can not be aware of moves).

Of course, not everyone has all myasthenic symptoms listed in the following list – there are fortunately many stakeholders who have only a few minor restrictions. And if someone e.g. has difficulty speaking, this means far from that then occur, all sorts of problems in speaking. And also the classic symptoms such as Diplopia and Ptosis occur not long since every Myasthenia Gravis patient. Of course some of Myasthenia Gravis symptoms can occur even in healthy individuals with fatigue and exhaustion when they occur but strikingly myasthenic gehauft and strong ausgepragt.

I have compiled this list (you can read at my next medical articles), because I have known for some of my problems after long years, they hang together with the MG, and because I hope to round off thereby the picture of the MG still another little. Let yourself from this list, so do not frighten, but read it with astonishment, look how different the Myasthenia Gravis can look.

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Posted by tata    Date: Wednesday, September 2, 2009

Categories: Myasthenia Gravis

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